The Effect of Consuming Stevia Liquid Extract (Steviol Glycosides) on Reducing Blood Sugar Levels in Patients With Type 2 Diabetes Mellitus

Authors

  • Eko Hermanto University of Medika Suherman
  • Try Pratama Nugraha University of Medika Suherman
  • Yulidian Pratiwi University of Medika Suherman
  • Mila Sartika University of Medika Suherman
  • Aprilina Sartika University of Medika Suherman

Keywords:

Diabetes Mellitus, Stevia Extract, Blood Sugar Level

Abstract

Diabetes Mellitus (DM) is a chronic metabolic disease characterized by high blood sugar levels due to impaired insulin production or use. The global prevalence of DM in 2021 reached 10.5% and is projected to increase to 12.2% by 2045. In Indonesia, the prevalence of DM in 2021 was recorded at 10.8% or around 19.5 million cases, while in Bekasi Regency, the prevalence of T2DM in 2022 reached 8.04% per 100 population. This study aims to evaluate the effect of Stevia (Steviol Glycosides) extract consumption on reducing blood sugar levels in T2DM patients. The research method used a quasi-experiment design with two group pre-post design, involving 76 T2DM patients who were divided into two groups, namely the intervention group given Stevia extract and the control group without treatment. The results of data analysis showed that before the intervention, there was a significant difference in blood sugar levels between the two groups (p = 0.000), with higher blood sugar levels in the intervention group. After the intervention, Stevia extract consumption was shown to significantly reduce blood sugar levels compared to the control group (p = 0.023). The conclusion of this study is that Stevia extract consumption has a significant effect on reducing blood sugar levels in T2DM patients, so it can be considered as a complementary therapy in the management of type 2 DM in the community.

Downloads

Download data is not yet available.

References

Barriocanal, L. A., Palacios, M., Benitez, G., & Benitez, S. (2024). Lack of effect of Stevia rebaudiana Bertoni on glucose homeostasis and insulin sensitivity in type 1 and type 2 diabetic subjects. Diabetes Care, 47(2), 377-383. https://doi.org/https://doi.org/10.33023/jpm.v10i1.1566.

Care, D., & Suppl, S. S. (2025). 6. Glycemic Goals and Hypoglycemia: Standards of Care in Diabetes—2025. Diabetes Care, 47(January), S111–S125. https://doi.org/10.2337/dc24-S006

Cohen, A. A. (2020). Aging across the tree of life: The importance of a comparative perspective for the use of animal models in aging. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1866(5), 165883. https://doi.org/10.1016/j.bbadis.2019.165883

Farhani, N. (2023). Pengaruh ekstrak cair Stevia terhadap penurunan kadar glukosa darah pada penderita diabetes melitus tipe 2. Jurnal Kesehatan Masyarakat, 18(2), 123-130. https://doi.org/https://doi.org/10.33023/jpm.v10i1.1566.

Hakim, L., Sari, D. P., & Utami, R. (2021). Dampak steviol glikosida pada glukosa darah puasa. Ensiklopedia of Journal, 3(5), 265-272. https://doi.org/https://doi.org/10.33023/jpm.v10i1.1566.

Mataputun, Donny Richard., at all (2024) Penyakit Endokrin. 1st edn. Edited by M.J.F. Sirait. Jakarta: Yayasan Kita Menulis. Available at: https://www.facebook.com/100063490032981/posts/957630406363285/?rdid=jcpg0FQEJDYjmMcO

Muthia, E. (2022). Pengaruh pemberian daun Stevia terhadap kadar glukosa darah pada penderita diabetes melitus tipe 2 di Desa Penyasawan. Jurnal Kesehatan, 14(1), 45-53. https://doi.org/https://doi.org/10.33023/jpm.v10i1.1566.

Nurrahman, A. I., Permadi, A. N., Safanah, A. N., Puspita, D. A., Anugrah, R., Putra, S. M., Ridwan, H., & Setiadi, D. K. (2025). Pengaruh Pemberian Ekstrak Daun Stevia Dalam Menjaga Kestabilan Kadar Gula Darah Penderita Diabetes. Intan Husada : Jurnal Ilmiah Keperawatan, 12(01), 121–141. https://doi.org/10.52236/ih.v12i1.517

Rahman, A., Permadi, A. N., Safanah, A. N., Puspita, D. A., & Rikman. (2021). Pengaruh pemberian ekstrak daun stevia dalam menjaga kestabilan kadar gula darah penderita diabetes. Jurnal Kesehatan Insada, 12(1), 45-53. https://doi.org/https://doi.org/10.33023/jpm.v10i1.1566.

Santika, E. F. (2025). Diabetes Tipe 2 Paling Banyak Diderita Orang Indonesia pada 2023. 2023, 15–16. https://databoks.katadata.co.id/datapublish/2025/07/26/diabetes-tipe-2-paling-banyak-diderita-orang-indonesia-pada-2023

Sartika, M., & Irawan, P. (2023). Hubungan Perilaku Sedentari Dengan Kadar Gula Darah Pada Pasien Diabetes Melitus di Rumah Sakit Sentra Medika Cikarang Tahun 2022. Jurnal Ilmiah Kesehatan. https://repository.medikasuherman.ac.id/xmlui/handle/123456789/5500.

Sartika, Mila., A. (2024) ‘Prevation of DPN ( Diabetic Peripheral Neuropathy) In Patients With Diabets Mellitus Type 2 In Mangunjaya Tambun Selatan’, Pengabdian Masyarakat Kesehatan Stikes Pemkab Jombang, X(1), pp. 8–13. Available at: https://doi.org/https://doi.org/10.33023/jpm.v10i1.1566.

Sartika, M. et al. (2023) ‘The Implementation of Hands and Feet Exercise Towards Pain Management Among DM Type II Patients with Peripheral Neuropathy in Indonesia’, Jurnal Keperawatan Komprehensif (Comprehensive Nursing Journal), 9(3). Available at: https://doi.org/10.33755/jkk.v9i3.508.

Sartika, M. and Armi (2023) ‘Faktor-Faktor Yang Berhubungan Dengan Prevalensi Diabetik Neuropati Periferal (DPN) Pada Pasien DM Tipe II Di Indonesia’, Jurnal Ilmiah Keperawatan (Scientific Journal of Nursing), 9(2), pp. 396–400. Available at: https://doi.org/10.33023/jikep.v9i2.1553.

Setiawan, A., & Putri, M. D. (2023). Potensi Stevia rebaudiana sebagai suplemen nondiabetik untuk menurunkan kadar glukosa darah. Prosiding Seminar Nasional, 5(1), 123-130. https://doi.org/https://doi.org/10.33023/jpm.v10i1.1566.

Setiawan, R., & Putri, D. A. (2023). Faktor-faktor yang mempengaruhi efektivitas Stevia dalam menurunkan kadar gula darah: Sebuah meta-analisis. Jurnal Penelitian Kesehatan, 25(1), 67-75. https://doi.org/10.52236/ih.v12i1.517

Downloads

Published

2025-12-16

How to Cite

Eko Hermanto, Try Pratama Nugraha, Yulidian Pratiwi, Mila Sartika, & Aprilina Sartika. (2025). The Effect of Consuming Stevia Liquid Extract (Steviol Glycosides) on Reducing Blood Sugar Levels in Patients With Type 2 Diabetes Mellitus. Jurnal Multidisiplin Sahombu, 5(08), 2656–2668. Retrieved from https://ejournal.seaninstitute.or.id/index.php/JMS/article/view/7665