Analysis of the Effectiveness of Avian Influenza Treatment in Humans: Literature Review

Rika Valensia; Indah Laily Hilmi; Salman Salman

Authors

Rika Valensia Universitas Singaperbangsa Karawang
Indah Laily Hilmi Universitas Singaperbangsa Karawang
Salman Salman Universitas Singaperbangsa Karawang

Keywords:

avian influenza, effectivity, oseltamivir

Abstract

Avian influenza is an influenza disease that is transmitted from birds, can transmit to humans and then can also be transmitted between humans, so that it can cause epidemics. Avian influenza is caused by a myxovirus virus that belongs to the Orthomyxoviridae family. This disease can be treated with antivirals and various other complementary drugs. These variations were then compared with a systematic literature review method to see which treatment had the best effect on treating avian influenza. The sample used in the research was taken from the population or individuals (case study). Results: most patients were treated with oseltamivir, some were given other antivirals and other additional treatments. Conclusion: treatment using the antiviral oseltamivir given ≤ 2 days after the onset of symptoms showed better treatment effectiveness than using other antivirals and corticosteroids.

References

A. Nashrullah and M. Kharis, “Pemodelan Sirs Untuk Penyakit Influenza Dengan Vaksinasi Pada Populasi Manusia Tak Konstan,” UNNES Journal of Mathematics, vol. 2, no. 1, pp. 46–54, 2013, doi: https://doi.org/10.15294/ujm.v2i1.1711.

K. Chávez Ramos et al., “Rapid, Sensitive, and Selective Detection of H5 Hemagglutinin from Avian Influenza Virus Using an Immunowall Device,” ACS Omega, vol. 4, no. 15, pp. 16683–16688, Oct. 2019, doi: 10.1021/acsomega.9b02788.

B. Taye et al., “A System Based-Approach to Examine Host Response during Infection with Influenza A Virus Subtype H7N9 in Human and Avian Cells,” Cells, vol. 9, no. 2, Feb. 2020, doi: 10.3390/cells9020448.

J. Zhou et al., “Biological features of novel avian influenza A (H7N9) virus,” Nature, vol. 499, no. 7459, pp. 500–503, 2013, doi: 10.1038/nature12379.

World Health Organization [WHO], “Avian Influenza Weekly Update Number 830 Human infection with avian influenza A(H5) viruses Human infection with avian influenza A(H5N1) virus,” Feb. 2022. [Online]. Available: https://www.who.int/teams/global-influenza-programme/avian-influenza/monthly-risk-assessment-

J. Friesenhagen et al., “Highly pathogenic influenza viruses inhibit inflammatory response in monocytes via activation of rar-related orphan receptor RORα,” J Innate Immun, vol. 5, no. 5, pp. 505–518, Jul. 2013, doi: 10.1159/000346706.

J. Lin et al., “An impedance immunosensor based on low-cost microelectrodes and specific monoclonal antibodies for rapid detection of avian influenza virus H5N1 in chicken swabs,” Biosens Bioelectron, vol. 67, pp. 546–552, May 2015, doi: 10.1016/j.bios.2014.09.037.

Kementerian Kesehatan Republik Indonesia, Pedoman Penanggulangan Flu Burung. Jakarta: Kemenkes RI, 2017. [Online]. Available: https://www.researchgate.net/publication/327414412

S. K. Jha, R. Thapa, P. K. Gupta, D. Neupane, S. Shrestha, and A. Gupta, “Knowledge, attitude and practice related to Avian influenza among poultry workers of Kathmandu, Nepal,” Int J Community Med Public Health, vol. 9, no. 1, p. 76, Dec. 2021, doi: 10.18203/2394-6040.ijcmph20214984.

D. A. Hewajuli, N. L. P. I. Dharmayanti, and I. W. T. Wibawan, “Deteksi, Isolasi, dan Identifikasi Avian influenza Subtipe H5N1 pada Unggas di Pulau Jawa, Indonesia Tahun 2016,” Jurnal Veteriner, vol. 18, no. 4, pp. 496–509, Feb. 2018, doi: 10.19087/jveteriner.2017.18.4.496.

P. K. S. Chan et al., “Determinants of antiviral effectiveness in influenza virus a subtype H5N1,” Journal of Infectious Diseases, vol. 206, no. 9, pp. 1359–1366, Nov. 2012, doi: 10.1093/infdis/jis509.

X. Qi et al., “Avian Influenza A(H7N9) Virus Infection in Pregnant Woman, China, 2013,” Emerg Infect Dis, vol. 20, no. 2, Feb. 2014, doi: 10.3201/eid2002.131109.

X. Tang et al., “ARDS associated with pneumonia caused by avian influenza A H7N9 virus treated with extracorporeal membrane oxygenation,” Clinical Respiratory Journal, vol. 9, no. 3, pp. 380–384, Jul. 2015, doi: 10.1111/crj.12140.

B. Cao et al., “Adjuvant corticosteroid treatment in adults with influenza a (H7N9) viral pneumonia,” Crit Care Med, vol. 44, no. 6, pp. e318–e328, Jun. 2016, doi: 10.1097/CCM.0000000000001616.

M. J. Ma et al., “Influenza A(H7N9) virus antibody responses in survivors 1 year after infection, China, 2017,” Emerg Infect Dis, vol. 24, no. 4, pp. 663–672, Apr. 2018, doi: 10.3201/eid2404.171995.

T. van Le et al., “Fatal avian influenza A(H5N1) infection in a 36-week pregnant woman survived by her newborn in Sóc Trăng Province, Vietnam, 2012,” Influenza Other Respir Viruses, vol. 13, no. 3, pp. 292–297, May 2019, doi: 10.1111/irv.12614.

V. Setiawaty, H. Apsari Pawestri, and Ketut Susilarini, “Deteksi Resistensi Oseltamivir Influenza A (H1N1pdm09) dari Pasien Infeksi Saluran Pernafasan Akut Berat di Indonesia tahun 2014,” Jurnal Kefarmasian Indonesia, vol. 6, no. 1, pp. 16–22, 2016.

M. A. Darmadi and G. Singh, “Efektivitas Kortikosteroid Sebagai Terapi Adjuvan Pada Pneumonia Komunitas Berat: Laporan Kasus Berbasis Bukti,” 2017.