Literature Review : In Silico Study Of Lung Anticancer Proteins

Authors

  • Alya Nafis Universitas Singaperbangsa Karawang, Indonesia
  • Fajar Prasetyo Universitas Singaperbangsa Karawang, Indonesia
  • Nur Sa’diyyah Universitas Singaperbangsa Karawang, Indonesia
  • Deviana Farhani Universitas Singaperbangsa Karawang, Indonesia
  • Nur Aenah Universitas Singaperbangsa Karawang, Indonesia

Keywords:

In silico studies, cancer, docking moleculer, review

Abstract

Cancer is a disease caused by rapid and uncontrolled cell proliferation. Cancer is a massive disease characterized by rapid and uncontrolled cell proliferation. Cancer cells will continue to affect other cells around them until all tissues with cancer damage organs and nerves. One type of cancer with high cases in Indonesia is lung cancer. This cancer is a type of tumor whose source is the epithelial lining of the bronchial lung branches. Generally, therapy for the treatment of lung cancer is radiation, chemotherapy, surgery, and hormone therapy. In silico testing is a type of study with a computational approach to predict the activity of potential compounds as drugs. This article uses a type of literature review research with a total of 15 reference materials indexed on Google Scholar.

References

R. Ruswanto, "SINTESIS DAN ANALISIS SPEKTRUM SENYAWA 3-BENZOIL-1-FENILTIOUREA SERTA UJI INTERAKSINYA PADA RESEPTOR KANKER," Jurnal Kesehatan Bakti Tunas Husada: Jurnal Ilmu-Ilmu Keperawatan, Analis Kesehatan dan Farmasi, vol. 12, no. 1, pp. 177-185, 2014.

N. Frimayanti, R. Dona and F. Cahyana, "Simulasi Molecular Dynamic (MD) Senyawa Analog Kalkon Sebagai Inhibitor Untuk Sel Kanker Paru A549," Jurnal Penelitian Farmasi Indonesia, vol. 9, no. 2, pp. 56-60, 2020.

E. Y. Mastura, M. T. Asri and E. R. Purnama, "Biokomputasi Aktivitas Senyawa D-alpha-Tocopherol dari Ekstrak Daun Zodia (Evodia suaveolens) sebagai Antikanker secara In Silico," LenteraBio: Berkala Ilmiah Biologi, vol. 9, no. 2, pp. 129-136, 2020.

Y. Wahyudi and D. Roza, "Docking Molekular Potensi Senyawa 2,6-Dimethylocta-3,5,7-Trien-2-Ol Terhadap Senyawa 4LL0 Anti Kanker Paru," in Prosiding Seminar Nasional Kimia & Pendidikan Kimia#2, Medan, 2021.

N. Frimayanti, M. Djohari and A. N. Khusnah, "Molekular Docking Senyawa Analog Kalkon sebagai Inhibitor untuk Sel Kanker Paru-Paru A549," Jurnal Ilmu Kefarmasian Indonesia, vol. 19, no. 1, pp. 87-95, 2021.

G. D. Sanora, E. Y. Mastura, M. O. M. Handoyono and E. R. Purnama, "AKTIVITAS SENYAWA 3,5,7- OCTATRIEN-2-OL, 2,6 DIMETHYL DARI EKSTRAK ZODIA SEBAGAI KANDIDAT OBAT ANTIKANKER PARU-PARU SECARA IN SILICO," in Seminar Nasional Biologi, Saintek, dan Pembelajarannya (SN-Biosper), Tasikmalaya, 2019.

R. Prasetiawati, Suherman, Meilia, Permana, Benny and Rahmawati, "Molecular Docking Study of Anthocyanidin Compounds Against Epidermal Growth Factor Receptor (EGFR) as Anti-Lung Cancer," Indonesian Journal of Pharmaceutical Science and Technology, vol. 8, no. 1, pp. 8-20, 2021.

Nazala, Syahrizal, Herawati, Diar and Fakih, Taufik Muhammad, "Uji In-Silico Aktivitas Antikanker Paru Senyawa Vanilloid Pada Jahe Merah (Zingiber officinale Roscoe.) Terhadap Epidermal Growth Factor Receptor (EGFR) EXON 20," in Bandung Conference Series: Pharmacy, Bandung, 2022.

Fadlan, Arif, Warsito, Tri and Sarmoko, "Studi In Silico Potensi Antikanker Senyawa Kaempferida," Alchemy: Journal of Chemistry, vol. 10, no. 1, pp. 14-21, 2022.

Pratama, Kelvin F, Fauzi, Muhammad and Hasanah, Aliya N, "Activity Screening and Structure Modification of Trigonelline as New Anticancer Drug for Non Small Cell Lung Cancer Through In Silico," Indonesian Journal of Pharmaceutical Science and Technology, vol. 7, no. 3, pp. 90-99, 2020.

Siagian, Dea Gracella and Roza, Destria, "Studi Molecular Docking Senyawa Antosianidin Dari Ekstrak Buah Jamblang (Syzygium cumini) Sebagai Senyawa Anti-Tumor Secara In Silico," in Prosiding Seminar Nasional Kimia & Pendidikan Kimia#2 , Medan, 2021.

Ananto, Agus Dwi, Muliasari, Handa and Handin, Candra Dwipayana, "Studi In Silico Bioaktivitas Antikanker Senyawa Aktif Dalam Minyak Biji Buah Wali [Brucea javanica (L.) Merr]," Sasambo Journal of Pharmacy, vol. 1, no. 2, pp. 26-29, 2020.

M. K. Rohmah, "STUDI IN SILICO KOMPLEKS LIGAND-RESEPTOR EUGENOL DAUN BASIL (Ocimum basilicum L.) DENGAN RESEPTOR HER2 PADA NON-SMALL CELL LUNG CANCER (NSCLC) DENGAN KONTROL GEFITINIB," Jurnal Ilmiah Medicamento, vol. 3, no. 2, pp. 71-78, 2017.

Subhani, Syed, Jayaraman, Archana and Jamil, Kaiser, "Homology modelling and molecular docking of MDR1 with chemotherapeutic agents in non-small cell lung cancer," Biomedicine & Pharmacotherapy, vol. 71, pp. 37-45, 2015.

Yuan, Chong, Wang, Meng-Heng, Wang, Fei, Chen, Peng-Yu, Ke, Xin Ge, Yu, Bing and Yang, Yan Fang, "Network pharmacology and molecular docking reveal the mechanism of Scopoletin against non-small cell lung cancer," Life Sciences, vol. 270, pp. 1-11, 2021.

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Published

2023-12-01

How to Cite

Alya Nafis, Fajar Prasetyo, Nur Sa’diyyah, Deviana Farhani, & Nur Aenah. (2023). Literature Review : In Silico Study Of Lung Anticancer Proteins. Jurnal EduHealth, 14(04), 429–438. Retrieved from https://ejournal.seaninstitute.or.id/index.php/healt/article/view/1103