Enhancement of Antioxidant and Colon Anticancer Activity from Fermented Rice Bran Extract
DOI:
https://doi.org/10.54209/jurnaleduhealth.v14i3.2597Keywords:
Antioxidant, Colon cancer, Fermentation, Rice branAbstract
This review focuses on the enhancement of antioxidant activity and the colon anticancer effect of fermented rice bran extract. Fermentation is a biological process that has been proven to significantly increase the content of bioactive compounds in various food sources, including rice bran. This study investigates how fermentation affects the antioxidant activity and colon anticancer potential of rice bran extract. The review highlights a positive correlation between phenolic content and antioxidant activity, indicating that fermented rice bran extract exhibits higher antioxidant properties compared to non-fermented ones. Additionally, this research explores the role of different fermentation microorganisms in promoting the release of phenolic compounds, contributing to increased antioxidant activity and colon anticancer effects. Understanding the potential health benefits of fermented rice bran extract can contribute to the development of functional food products with improved nutritional and therapeutic effects
References
Worrld Health Organization, Cancer. 2015. Accessed: Jun. 07, 2023. [Online]. Available: : http://www.who.int/mediacentre/factsheets
International Agency for Research on Cancer, “The Global Cancer Observatory. Indonesia Source: Globocan 2020,” International Agency for Research on Cancer, 2020. https://gco.iarc.fr/today/data/factsheets/populations/900-world-fact-sheets.pdf (accessed Jun. 07, 2023).
A. J. Henderson et al., “Chemopreventive properties of dietary rice bran: Current status and future prospects,” Advances in Nutrition, vol. 3, no. 5. 2012. doi: 10.3945/an.112.002303.
G. M. Forster et al., “Rice varietal differences in bioactive bran components for inhibition of colorectal cancer cell growth,” Food Chem, vol. 141, no. 2, 2013, doi: 10.1016/j.foodchem.2013.04.020.
K. Zulfafamy, Ardiansyah, and S. Budijanto, “Current Research in Nutrition and Food Science Antioxidative Properties and Cytotoxic Activity against Colon Cancer Cell WiDr of Rhizopus oryzae and Rhizopus,” Current Research in nutrition and Food science, vol. 6, no. 1, 2018.
Faizah, F. Kusnandar, and S. Nurjanah, “Senyawa fenolik, oryzanol, dan aktivitas antioksidan bekatul yang difermentasi dengan Rhizopus oryzae,” Jurnal Teknologi dan Industri Pangan , vol. 31, no. 1, pp. 86–94, Jun. 2020.
Safrida et al., “Fermented black rice bran extract inhibit colon cancer proliferation in WiDr cell lines,” Food Science and Technology (Brazil), vol. 42, 2022, doi: 10.1590/fst.14422.
S. Sapwarobol, W. Saphyakhajorn, and J. Astina, “Biological Functions and Activities of Rice Bran as a Functional Ingredient: A Review,” Nutrition and Metabolic Insights, vol. 14. 2021. doi: 10.1177/11786388211058559.
M. Sohail, A. Rakha, M. S. Butt, M. J. Iqbal, and S. Rashid, “Rice bran nutraceutics: A comprehensive review,” Crit Rev Food Sci Nutr, vol. 57, no. 17, 2017, doi: 10.1080/10408398.2016.1164120.
S. Hartati, Y. Marsono, and U. Santoso, “Komposisi Kimia Serta Aktivitas Antioksidan Ekstrak Hidrofilik Bekatul Beberapa Varietas Padi,” Jurnal Agritech, vol. 35, no. 1, 2015.
S. P. Kim, M. Y. Kang, S. H. Nam, and M. Friedman, “Dietary rice bran component γ-oryzanol inhibits tumor growth in tumor-bearing mice,” Mol Nutr Food Res, vol. 56, no. 6, 2012, doi: 10.1002/mnfr.201200057.
B. Janicke et al., “The antiproliferative effect of dietary fiber phenolic compounds ferulic acid and p-coumaric acid on the cell cycle of Caco-2 cells,” Nutr Cancer, vol. 63, no. 4, 2011, doi: 10.1080/01635581.2011.538486.
N. N. Putri, S. Budijanto, E. Prangdimurti, and B. Pontjo, “Bekatul Beras Hitam Terfermentasi Memperbaiki Kondisi Kolon Mencit yang Diinduksi Senyawa Karsinogen Azoxymethane,” Jurnal Teknologi dan Industri Pangan, vol. 34, no. 1, 2023, doi: 10.6066/jtip.2023.34.1.13.
L. Tajasuwan, A. Kettawan, T. Rungruang, K. Wunjuntuk, and P. Prombutara, “Role of Dietary Defatted Rice Bran in the Modulation of Gut Microbiota in AOM/DSS-Induced Colitis-Associated Colorectal Cancer Rat Model,” Nutrients, vol. 15, no. 6, 2023, doi: 10.3390/nu15061528.
R. J. Singh et al., “Universidade Federal Do Rio Grande Do Sul Instituto De Ciências Básicas Da Saúde Programa De Pós-Graduação Em Microbiologia Agrícola E Do Ambiente,” Bioresour Technol, vol. 6, no. 3, 2018.
S. Kumar, “the Importance of Antioxidant and Their Role in Pharmaceutical Science - a Review,” Asian Journal of Research in Chemistry and Pharmaceutical Sciences, vol. 1, no. 1, 2014.
K. Atjanasuppat et al., “In vitro screening for anthelmintic and antitumour activity of ethnomedicinal plants from Thailand,” J Ethnopharmacol, vol. 123, no. 3, 2009, doi: 10.1016/j.jep.2009.03.010.
S. Budijanto et al., “Dietary Supplementation of Black Rice Bran to Colon Carcinogen-Induced Mice: Examining the Development of Colorectal Cancer by Improving Environmental Colon Conditions,” SSRN Electronic Journal, 2022, doi: 10.2139/ssrn.4263988.
