Analysis Of The Relationship Of Covid-19 Vaccination Status With Hematological Features In Pregnant Women

Authors

  • Helena Rugun Nauli Nainggolan Departemen Parasitologi Fakultas Kedokteran Universitas HKBP Nommensen Medan
  • Leo Jumadi Simanjuntak Departemen Obstetri Ginekologi Fakultas Kedokteran Universitas HKBP Nommensen Medan
  • Gerald Osson Fransiska Siahaan Mahasiswa Fakultas Kedokteran Universitas HKBP Nommensen Medan

Keywords:

Covid-19, Covid-19 Vaccination, Hematology

Abstract

Background:Pregnant women are a group that is vulnerable to being infected with Covid-19, and this has an impact on increasing the risk of maternal outcomes with Covid-19. According to the Indonesian government's policy, pregnant women can be given Covid-19 vaccinations, including the Pfizer and Moderna mRNA platforms, and the Sinovac inactivated platform vaccine. Pregnant women who have been vaccinated against Covid-19 will be less likely to suffer from Covid-19, thereby reducing the risk of complications for the mother and baby. Hematology images can assess prognosis, and predict and monitor the course of disease due to Covid-19. Purpose:To determine the relationship between Covid-19 vaccination status and the average levels of hemoglobin, platelets, leukocytes, lymphocytes, and the ratio of neutrophils to lymphocytes in women giving birth at Herna Hospital and Mitra Sejati Hospital, Medan. Methods: The research design used was descriptive-analytical with a cross-sectional approach used to analyze the relationship between Covid-19 vaccination status and the hematological features of third-trimester pregnant women who will give birth by cesarean section. This research was carried out at Herna General Hospital and Mitra Sejati Hospital in Medan. The inclusion criteria were full-term pregnancy, no complications during pregnancy, and willing to take part in the research and the exclusion criteria were unclear Covid-19 vaccination status. Analysis of the research data with the Chi-square test. Results:Based on the research results, from 190 samples of pregnant women, there were no significant differences in vaccination status based on hematological parameters, age, and gravida. Conclusion: Based on the research results, it can be concluded that there is no relationship between Covid-19 vaccination status and hematological features in pregnant women.

References

Peraturan Menteri Kesehatan Republik Indonesia Nomor 19 Tahun 2021 Tentang Perubahan Kedua Atas Peraturan Menteri Kesehatan Nomor 10 Tahun 2021 Tentang Pelaksanaan Vaksinasi Dalam Rangka Penanggulangan Pandemi Corona Virus Disease 2019 (Covid-19)

Perkumpulan Obstetri dan Ginekologi Indonesia (POGI), Rekomendasi POGI terkait dengan melonjaknya kasus ibu hamil dengan Covid-19 dan perlindungan terhadap tenaga kesehatan, 2021.

CDC, COVID-19 Vaccines While Pregnant or Breastfeeding, 2022, available from CDC.gov

Dirjen Pencegahan Dan Pengendalian Penyakit Ri, Surat Edaran Hk.02.01/1/ /2021 Tentang Vaksinasi Covid-19 Bagi Ibu Hamil Dan Penyesuaian Skrining Dalam Pelaksanaan Vaksinasi Covid-19

Qin C,Zhou ,Hu Z, Zhang S,Yang S,Taoy,etal. Dysregulation of immune response in patients with CovID-19 in Wuhan, China. Clin Infect Dis. 2020;ciaa248.

Magnus, MC, Örtqvist, AK, Dahlquist,E, Ljung, R, Skar, F, Oakley L et al. 2022, Association of SARS-CoV-2 Vaccination During Pregnancy With Pregnancy Outcomes, JAMA. doi:10.1001/jama.2022.3271 Published online March 24, 2022.

Fell, DB, Dhinsa, T, Alton,GD, Torok, E, Dimanlig-Cruz, S, Regan, AK, et al. 2022 Association of COVID-19 Vaccination in Pregnancy With Adverse Peripartum Outcomes, JAMA. doi:10.1001/jama.2022.4255 Published online March 24, 2022.

Pertiwi RD, Ayubi D. Hubungan Pengetahuan dengan Status Vaksinasi COVID-19 pada Ibu Hamil di Wilayah DKI Jakarta. Media Publ Promosi Kesehat Indones. 2022;5(4):395–403.

Wisdayanti S, Sulistyowati S. Profil Laboratorium Ibu Hamil dengan COVID-19 di Rumah Sakit UNS. SMedJour. 2021;4(2):83–7.

Theiler RN, Wick M, Mehta R, et al. Pregnancy and birth outcomes after SARS-CoV-2 vacci- nation in pregnancy. Am J Obstet Gynecol MFM 2021;3:100467.

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Published

2023-03-30

How to Cite

Helena Rugun Nauli Nainggolan, Leo Jumadi Simanjuntak, & Gerald Osson Fransiska Siahaan. (2023). Analysis Of The Relationship Of Covid-19 Vaccination Status With Hematological Features In Pregnant Women. Jurnal EduHealth, 14(01), 534–537. Retrieved from https://ejournal.seaninstitute.or.id/index.php/healt/article/view/2908