Is It True That Intravesical Prostatic Protrusion Affects The International Prostatic Symptom Score In Patients With Benign Prostate Enlargement?

Authors

  • Farras Arsyi Addaruqutni Prodi Pendidikan Dokter, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Muhammadiyah Yogyakarta, Indonesia
  • Ana Majdawati Departemen Radiologi Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Muhammadiyah Yogyakarta, Indonesia
  • Bernardus Bona Wisesa Prodi Pendidikan Dokter, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Muhammadiyah Yogyakarta, Indonesia
  • Ageng Setya Budi Mazaya Prodi Pendidikan Dokter, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Muhammadiyah Yogyakarta, Indonesia

Keywords:

Benign prostatic hyperplasia, intravesical prostatic protrusion, international prostatic symptom score, transabdominal, ultrasonography

Abstract

Benign Prostatic Hyperplasia (BPH), also known as benign prostate enlargement, is among the most common benign tumors affecting men, with a prevalence and incidence that increases with age, categorized as one of the genitourinary issues. In Indonesia, there are 9.2 million reported cases of BPH in men over 60 years old. Intravesical Prostatic Protrusion (IPP) is one manifestation of Benign Prostatic Hyperplasia (BPH) development. Patient complaints associated with Benign Prostatic Hyperplasia (BPH) can be assessed through the International Prostatic Symptom Score (IPSS). This study aims to investigate the potential relationship between Intravesical Prostatic Protrusion (IPP) and patient complaints assessed by the International Prostatic Symptom Score (IPSS) in individuals diagnosed with BPH. This research employed an observational cross-sectional study design and utilized the chi-square correlation test. Data from 67 Benign Prostatic Hyperplasia (BPH) patients, all displaying prostate protrusion, were categorized into three groups based on the degree of protrusion observed on prostate ultrasound: grade I, grade II, and grade III. IPSS scores were measured using the Indonesian version of the IPSS questionnaire, where patients self-assessed their symptoms and were categorized into mild, moderate, or severe groups. Analysis using the chi-square correlation test revealed a p-value of 0.208, signifying the obtained p-value > 0.05. This suggests that no statistically significant relationship was found between the variables under investigation. The study concludes no significant relationship exists between Intravesical Prostatic Protrusion (IPP) and the International Prostatic Symptom Score (IPSS) in individuals diagnosed with Benign Prostatic Hyperplasia (BPH).

References

Devlin, C. M., Simms, M. S., & Maitland, N. J. (2021). Benign prostatic hyperplasia–what do we know? BJU International, 127(4), 389–399.

Giri, A., Edwards, T. L., Motley, S. S., Byerly, S. H., & Fowke, J. H. (2015). Genetic Determinants of Metabolism and Benign Prostate Enlargement: Associations with Prostate Volume. PLOS ONE, 10(7), e0132028. https://doi.org/10.1371/journal.pone.0132028

Hellwege, J. N., Stallings, S., Torstenson, E. S., Carroll, R., Borthwick, K. M., Brilliant, M. H., Crosslin, D., Gordon, A., Hripcsak, G., Jarvik, G. P., Linneman, J. G., Devi, P., Peissig, P. L., Sleiman, P. A. M., Hakonarson, H., Ritchie, M. D., Verma, S. S., Shang, N., Denny, J. C., … Edwards, T. L. (2019). Heritability and genome-wide association study of benign prostatic hyperplasia (BPH) in the eMERGE network. Scientific Reports, 9, 6077. https://doi.org/10.1038/s41598-019-42427-z

Jindal, T., Sinha, R., Mukherjee, S., Mandal, S., & Karmakar, D. (2014). Misinterpretation of the international prostate symptom score questionnaire by Indian patients. Indian Journal of Urology, 30(3), 252. https://doi.org/10.4103/0970-1591.134246

Lee, L. S., Sim, H. G., Lim, K. B., Wang, D., & Foo, K. T. (2010). Intravesical prostatic protrusion predicts clinical progression of benign prostatic enlargement in patients receiving medical treatment: IPP and progression of BPE. International Journal of Urology, 17(1), 69–74. https://doi.org/10.1111/j.1442-2042.2009.02409.x

Lokeshwar, S. D., Harper, B. T., Webb, E., Jordan, A., Dykes, T. A., Neal, D. E., Terris, M. K., & Klaassen, Z. (2019). Epidemiology and treatment modalities for the management of benign prostatic hyperplasia. Translational Andrology and Urology, 8(5), 529–539. https://doi.org/10.21037/tau.2019.10.01

Madersbacher, S., Sampson, N., & Culig, Z. (2019). Pathophysiology of Benign Prostatic Hyperplasia and Benign Prostatic Enlargement: A Mini-Review. Gerontology, 65(5), 458–464. https://doi.org/10.1159/000496289

McVary, K. T., Roehrborn, C. G., Avins, A. L., Barry, M. J., Bruskewitz, R. C., Donnell, R. F., Foster, H. E., Gonzalez, C. M., Kaplan, S. A., Penson, D. F., Ulchaker, J. C., & Wei, J. T. (2011). Update on AUA Guideline on the Management of Benign Prostatic Hyperplasia. Journal of Urology, 185(5), 1793–1803. https://doi.org/10.1016/j.juro.2011.01.074

Monoarfa, A., Aschorijanto, A., Monoarfa, R., & Tubagus, V. (2017). Hubungan antara intravesical prostatic protrution, International prostatic symptom score, dan uroflowmetry pada kasus benign prostatic hyperplasia di RSUP Prof. Dr. RD Kandou Manado. Jurnal Biomedik: JBM, 9(2).

Nickel, J. C., Freedland, S. J., Castro-Santamaria, R., & Moreira, D. M. (2017). Chronic prostate inflammation predicts symptom progression in patients with chronic prostatitis/chronic pelvic pain. The Journal of Urology, 198(1), 122–128.

Nickel, J. C., Méndez-Probst, C. E., Whelan, T. F., Paterson, R. F., & Razvi, H. (2010). 2010 Update: Guidelines for the management of benign prostatic hyperplasia. 4(5), 7.

Roehrborn, C. G. (2005). Benign Prostatic Hyperplasia: An Overview. 12.

Sebastianelli, A., & Gacci, M. (2018). Current status of the relationship between metabolic syndrome and lower urinary tract symptoms. European Urology Focus, 4(1), 25–27.

Song, L., Shen, W., Zhang, H., Wang, Q., Wang, Y., & Zhou, Z. (2016). Differential expression of androgen, estrogen, and progesterone receptors in benign prostatic hyperplasia. Bosnian Journal of Basic Medical Sciences, 16(3), 201–208. https://doi.org/10.17305/bjbms.2016.1209

Tangel, S. J. Ch., Monoarfa, A., & Monoarfa, R. A. (2019). Validasi International Prostate Symptom Score Versi Bahasa Indonesia pada Penderita Lower Urinary Tract Symptoms di Poliklinik Urologi RSUP Prof. Dr. R. D. Kandou Manado. JURNAL BIOMEDIK (JBM), 11(2), 92. https://doi.org/10.35790/jbm.11.2.2019.23320

Tjahjojati, J. (2014). Protrusion, International Prostatic Symptom Score, and Uroflowmetry. International Journal of Integrated Health Sciences.

Wang, D., Huang, H., Law, Y. M., & Foo, K. T. (2015). Relationships between Prostatic Volume and Intravesical Prostatic Protrusion on Transabdominal Ultrasound and Benign Prostatic Obstruction in Patients with Lower Urinary Tract Symptoms. Annals of the Academy of Medicine, Singapore, 44(2), 60–65. https://doi.org/10.47102/annals-acadmedsg.V44N2p60

Downloads

Published

2023-12-29

How to Cite

Farras Arsyi Addaruqutni, Ana Majdawati, Bernardus Bona Wisesa, & Ageng Setya Budi Mazaya. (2023). Is It True That Intravesical Prostatic Protrusion Affects The International Prostatic Symptom Score In Patients With Benign Prostate Enlargement?. Jurnal EduHealth, 14(04), 733–738. Retrieved from https://ejournal.seaninstitute.or.id/index.php/healt/article/view/3682