Formulation of Antiaging Activities in Creams Made From Natural Active Ingredients
Keywords:
antiaging, cream, formulation, natural ingredientsAbstract
Anti-aging treatments have become a major focus in the beauty industry, with anti-aging creams being one of the most sought after products to treat the signs of skin aging. This cream is formulated with the aim of inhibiting the premature aging process, reducing the appearance of wrinkles, and disguise skin imperfections. Natural ingredients with antioxidant activity have been in the spotlight in the development of anti-aging cream formulations, due to their ability to fight skin damage caused by free radicals. In an effort to identify effective cream formulations, the literature review method was used to evaluate various relevant reference sources. This literature review revealed several natural ingredients that have anti-aging potential, such as tamarind leaf extract, banana peel, purple eggplant, and moringa leaves, as well as ylang-ylang oil and lemon oil. In addition, fruits such as rambutan and lemon, as well as red spinach leaves, also stand out for their high antioxidant content, including vitamin C and lycopene. This research provides insight into the various natural ingredients that can be used in anti-aging cream formulations, leading to the development of more effective and environmentally friendly products in caring for skin.
References
Amin, N. Y. A., Naspiah, N., & Rusli, R. (2018). Formulasi Sediaan Krim Anti Aging Berbahan Aktif Ekstrak Buah Libo (Ficus Variegata, Blume). Proceeding of the 8th Mulawarman Pharmaceuticals Conferences, November 2018, 20–21.
Ammar, H. O., Ghorab, M. M., Mostafa, D. M., & Ibrahim, E. S. (2016). Folic acid loaded lipid nanocarriers with promoted skin antiaging and antioxidant efficacy. Journal of Drug Delivery Science and Technology, 31, 72–82. https://doi.org/https://doi.org/10.1016/j.jddst.2015.11.007
Bertran, A., Martínez, A., Gómez, S., Pérez, M., Pascual, S., Luis, L., & González, M. (2022). 519 Design of a new molecule proven to be safe and effective for topical depigmenting and antiaging method. Journal of Investigative Dermatology, 142(12, Supplement), S270. https://doi.org/https://doi.org/10.1016/j.jid.2022.09.534
Cecchi, L., Bellumori, M., Cipriani, C., Mocali, A., Innocenti, M., Mulinacci, N., & Giovannelli, L. (2018). A two-phase olive mill by-product (pâté) as a convenient source of phenolic compounds: Content, stability, and antiaging properties in cultured human fibroblasts. Journal of Functional Foods, 40, 751–759. https://doi.org/https://doi.org/10.1016/j.jff.2017.12.018
Chu, C. C., Hasan, Z. A. B. A., Tan, C. P., & Nyam, K. L. (2021). In Vitro Antiaging Evaluation of Sunscreen Formulated from Nanostructured Lipid Carrier and Tocotrienol-Rich Fraction. Journal of Pharmaceutical Sciences, 110(12), 3929–3936. https://doi.org/https://doi.org/10.1016/j.xphs.2021.08.020
Hemagirri, M., & Sasidharan, S. (2022). In vitro antiaging activity of polyphenol rich Polyalthia longifolia (Annonaceae) leaf extract in Saccharomyces cerevisiae BY611 yeast cells. Journal of Ethnopharmacology, 290, 115110. https://doi.org/https://doi.org/10.1016/j.jep.2022.115110
Huerta-Madroñal, M., Espinosa-Cano, E., Aguilar, M. R., & Vazquez-Lasa, B. (2023). Antiaging properties of antioxidant photoprotective polymeric nanoparticles loaded with coenzyme-Q10. Biomaterials Advances, 145, 213247. https://doi.org/https://doi.org/10.1016/j.bioadv.2022.213247
Hwang, E., Park, S.-Y., Yin, C. S., Kim, H.-T., Kim, Y. M., & Yi, T. H. (2017). Antiaging effects of the mixture of Panax ginseng and Crataegus pinnatifida in human dermal fibroblasts and healthy human skin. Journal of Ginseng Research, 41(1), 69–77. https://doi.org/https://doi.org/10.1016/j.jgr.2016.01.001
Jannah, A. M., & Aznam, N. (2022). The Formulation and Evaluation of Anti-Aging Tamarind Leaf (Tamarindus Indica L.) Extract Cream. Indonesian Journal of Chemistry and Environment, 5(2), 68–78. https://doi.org/10.21831/ijoce.v5i2.58395
Leoty-okombi, S., Gault, M., & Andre-Frei, V. (2022). 240 Lactobacillus crispatus probiotic for skin antiaging benefits. Journal of Investigative Dermatology, 142(12, Supplement), S221. https://doi.org/https://doi.org/10.1016/j.jid.2022.09.251
Maimunah, S., Nasution, Z., Farmasi, F., & Sari, U., & Indonesia, M. (2020). Pemanfaatan Ekstrak Daun Urtica Dioica L. Sebagai Anti-Aging Alami Dalam Sediaan Krim. Jurnal Penelitian Saintek, 25(2), 124–134.
Meza, D., Patel, R., Rahim, A., Tang, M., Tan, J., Tan, W. N., Zhang, J., & Parsa, R. (2021). 27885 An optimized formulation of retinol with a specific sensory profile upregulates antiaging biomarkers for both prevention and rejuvenation of the skin. Journal of the American Academy of Dermatology, 85(3, Supplement), AB165. https://doi.org/https://doi.org/10.1016/j.jaad.2021.06.673
Nurhadianty, V., Brahmanti, H., Murlistyarini, S., & Cahyani, C. (2021). Formulasi Krim Anti-Aging Pada Kulit Daerah Tropis Berbasis Ekstrak Daun Kelor, Minyak Kenanga Dan Minyak Lemon Sebagai Bioaktif. Journal of Innovation and Applied Technology, 7(1), 1166–1172. https://doi.org/10.21776/ub.jiat.2021.007.01.7
Paul, P., Shaw, T. K., Mallick, A., Dhar, A., & Kanu, A. (2022). Chapter 9 - Lipid-based nanocosmeceuticals with antiaging potential (M. K. B. T.-N. Das (ed.); pp. 277–305). Academic Press. https://doi.org/https://doi.org/10.1016/B978-0-323-91077-4.00019-3
Peslak, M. E., Hawkins, S. S., Lee, C., Nicoletti, M., Truong, H., Bekto, H., & Wolcheski, J. (2022). 33252 Novel antiaging retinol complex improves facial photodamage in a Hispanic and Caucasian population. Journal of the American Academy of Dermatology, 87(3, Supplement), AB187. https://doi.org/https://doi.org/10.1016/j.jaad.2022.06.779
Ratnasari, D., & Puspitasari, R. N. (2018). Optimasi Formula Sediaan Krim Anti-Aging Dari Ekstrak Terong Ungu (Solanum melongena L.) Dan Tomat (Solanum lycopersicum L.). Jurnal Riset Kesehatan, 7(2), 66.
Rezky Putri, A., Suhartinah, S., & Kartika, M. (2023). Uji Aktivitas Krim Anti-Aging Ekstrak Etanol Daun Bayam Merah (Amaranthus tricolor L.) pada Kulit Punggung Kelinci New Zealand yang dipapar Sinar UV-A. Indonesian Journal of Pharmaceutical Education, 3(1), 1–15. https://doi.org/10.37311/ijpe.v3i1.18809
Rouvrais, C., Bacqueville, D., Bogdanowicz, P., Haure, M., Duprat, l, Coutanceau, C., Castex-Rizzi, N., Duplan, H., Mengeaud, V., & Bessou-Touya, S. (2017). 647 Assessment of antiaging properties of retinaldehyde, delta-tocopherol glucoside and glycylglycine oleamide combination. Journal of Investigative Dermatology, 137(10, Supplement 2), S303. https://doi.org/https://doi.org/10.1016/j.jid.2017.07.323
Rouvrais, C., Bacqueville, D., Patrick, B., Haure, M., Duprat, L., Coutanceau, C., Castex-Rizzi, N., Hélène, D., Mengeaud, V., & Bessou-Touya, S. (2017). 552 Assessment of antiaging properties of retinaldehyde/delta-tocopherol glucoside/glycylglycine oleamide combination. Journal of Investigative Dermatology, 137(5, Supplement 1), S95. https://doi.org/https://doi.org/10.1016/j.jid.2017.02.573
Ruangchuay, S., Wang, Q., Wang, L., Lin, J., Wang, Y., Zhong, G., Maneenoon, K., Huang, Z., & Chusri, S. (2021). Antioxidant and antiaging effect of traditional Thai rejuvenation medicines in Caenorhabditis elegans. Journal of Integrative Medicine, 19(4), 362–373. https://doi.org/https://doi.org/10.1016/j.joim.2021.03.004
Science, H., & Alaaddin, A. (2022). Fatih Uckaya ,. 13(1), 181–191. https://doi.org/10.13040/IJPSR.0975-8232.13(1).181-91
Sekar, M., Sivalinggam, P., & Mahmad, A. (2017). Formulation and Evaluation of Antiaging Cream Containing Rambutan Fruits Extract. International Research Journal Of Pharmaeutical Sciences and Research, 8(3), 1056–1065.
Sharma, G., & John, J. (2023). Identification of polyphenols using UPLC-QTOF MS/MS, in-vitro photoprotective and antiaging activities of brown macroalga Padina tetrastromatica. Algal Research, 75, 103255. https://doi.org/https://doi.org/10.1016/j.algal.2023.103255
Silalahi, Y. C. E., Zuhairiah, Sinaga, E. M., & Sitohang, I. K. (2019). Formulasi Krim Anti- Aging Dari Ekstrak Kulit Buah Jeruk (Citruslimon). FARMANESIA, 6(1), 1–10.
Song, Q., Zhou, X., Xu, K., Liu, S., Zhu, X., & Yang, J. (2023). The Safety and Antiaging Effects of Nicotinamide Mononucleotide in Human Clinical Trials: an Update. Advances in Nutrition, 14(6), 1416–1435. https://doi.org/https://doi.org/10.1016/j.advnut.2023.08.008
Sugihartini, N., & Nuryanti, E. (2017). Formulasi Krim Ekstrak Daun Kelor (Moringa oleifera) sebagai Sediaan Antiaging. Berkala Ilmu Kesehatan Kulit Dan Kelamin, 29(1), 1–7.
Sutopo, & Sugiyono. (2021). Metode penelitian kuantitatif kualitatif dan R dan D. Bandung : Afabeta.
Younis, I. Y., Farag, M. A., Elgamal, A. M., & Mohsen, E. (2023). Untargeted metabolites profiling of volatile and non-volatile components of Egyptian lotus (Nelumbo nucifera Gaertn.) using UHPLC/PDA/ESI-MS and solid-phase microextraction (SPME) GC/MS in relation to its antiaging and anti-inflammatory effects. Industrial Crops and Products, 197, 116561. https://doi.org/https://doi.org/10.1016/j.indcrop.2023.116561
