Effectiveness Test Of Face Wash Gel Kersen Leaf (Muntingia Calabura) Thick Extract As Anti-Acne Agent
Keywords:
Face wash gel, Staphyloccus aureus, Acne vulgari, Muntingia calaburaAbstract
Acne Vulgaris or acne is a skin disease caused by a blockage in the pores of the skin that causes oil secretion to be inhibited which will increasingly enlarge and experience inflammation and bacterial activity. One of the bacteria that can trigger acne is Stapyloccus aureus. Kersen plant is one of the plants that have properties as antibacterial. face wash gel is a facial cleanser with a gel base that contains foam, usually used for sensitive, oily and acne skin. Investigating the antibacterial properties of the Kersen plant may offer a potential treatment strategy. Additionally, the physical tests of gel-based face washe warrant further exploration. The purpose of this study was to see the effect of carbopol on the preparation and also to see the concentration of kersen leaf extract that can inhibit S.aureus bacteria. Preparation was done by dissolving kersen leaf extract with ethanol. Then in a separate place, Carbopol was developed with warm water (40-50°C) until it expanded. Then in a glass beaker dissolved propyl paraben, methyl paraben and SLS with distilled water and added Carbopol that has expanded stir until homogeneous and formed a gel base. Then Kersen leaf extract was added and stirred until homogeneous and TEA was added little by little along with stirring until homogeneous. Physical tests were carried out including organoleptic tests by observing the aroma, color and shape, testing the pH of the preparation with universal pH paper, testing the foam height of the preparation, testing the viscosity with a Brookfield viscometer, testing homogeneity and conducting bacterial activity tests with the paper disk method. The results obtained by the preparation of face wash gel of kersen leaf extract with F0-F2 obtained preparations that have a cloudy, light brown and dark brown color. It has a kersen smell with the addition of kersen and its texture from liquid to thick. The preparation has a pH of 7 and is homogeneous, has a viscosity that meet the requirements. The foam height of the preparation is in the range of 8.9 cm - 9.2 cm, which meets the requirements. In the activity test results, it was found that F2 with an extract concentration of 0.5 g had a better inhibition zone of 60 mm.
References
Andini, D., Mulangsri, K., & Zulfa, E. (2020). Uji Aktivitas Antibakteri Ekstrak Terpurifikasi Daun Mangga Arumanis (Mangifera indica L.) dan Identifikasi Flavonoid dengan KLT: Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal), 6(1), 55–62. https://doi.org/10.22487/J24428744.2020.V6.I1.14044
Asriani Safitri, E., Fatmawati, A., & Ilmu-Ilmu Kesehatan, F. (2021). PHARMACEUTICAL JOURNAL OF INDONESIA Aktivitas Inhibisi Ekstrak Etanolik Ulva lactuca terhadap Bakteri Staphylococcus aureus. In PHARMACEUTICAL JOURNAL OF INDONESIA 2021 (Vol. 7, Issue 1). http://.pji.ub.ac.id
Auliya Zulfa, A., Yuniarsih, N., Faomasi Gulo, A., Fathurrohmah, A., Amirulloh, N., & Salma Dhaniaty, S. (2023). Literature Review Article : Sabun Muka Tomat (Solanum Lycopersicum) Sebagai Antioksidan. Jurnal Multidisiplin Indonesia, 2(6), 904–910. https://doi.org/10.58344/JMI.V2I6.239
Ayunda, M., & Rosalina, L. (2023). Kelayakan Sediaan Sampo Daun Jarak Pagar (Jatropha Curcas L.) untuk Perawatan Rambut. Jurnal Pendidikan Tambusai, 7(2), 15927–15937. https://doi.org/10.31004/JPTAM.V7I2.8888
Feronica Manik, D., Hertiani, T., Anshory, H., & Mada, G. (n.d.). ANALISIS KORELASI ANTARA KADAR FLAVONOID DENGAN AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAN FRAKSI-FRAKSI DAUN KERSEN (Muntingia calabura L.) TERHADAP Staphylococcus aureus.
Genatrika, E., Nurkhikmah, I., & Hapsari, I. (2016). FORMULASI SEDIAAN KRIM MINYAK JINTAN HITAM (Nigella sativa L.) SEBAGAI ANTIJERAWAT TERHADAP BAKTERI Propionibacterium acnes. PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia), 13(02), 192–201. https://doi.org/10.30595/PJI.V13I02.1256
Joshi, J., Bhandari, D. P., Ranjitkar, R., Bhandari, L., & Yadav, P. M. (2019). Formulation and Evaluation of Herbal Soap, Shampoo and Face Wash Gel. In Journal of Plant Resources (Vol. 17, Issue 1).
Jumardin, W., Firdaus, S., & Utari, A. U. (2023). Formulasi dan Uji Aktivitas Antibakteri Sediaan Gel Facial Wash Ekstrak Etanol Daun Belimbing Wuluh (Averrhoa Bilimbi L.) Terhadap Pertumbuhan Propionibacterium Acnes Penyebab Jerawat. INHEALTH : INDONESIAN HEALTH JOURNAL , 2(2), 153~169-153~169. https://doi.org/10.56314/INHEALTH.V2I2.156
Kajornwongwattana W, & Suksaeree J. (2016). Formulation of face wash gel containing Thai herbal extract self-microemulsifying system. In Thai Journal of Pharmaceutical Sciences (TJPS) Journal homepage (Vol. 40). http://www.tjps.pharm.chula.ac.th
Khairunnisa, K., Budi, S., & Rohama, R. (2023). Formulasi Dan Uji Stabilitas Fisik Facial Wash Ekstrak Daun Sepat (Mitragyna Speciosa Kroth). Innovative: Journal Of Social Science Research, 3(5), 9832–9841. https://doi.org/10.31004/INNOVATIVE.V3I5.6059
Lestari, R. T., Gifanda, L. Z., Kurniasari, E. L., Harwiningrum, R. P., Kelana, A. P. I., Fauziyah, K., Widyasari, S. L., Tiffany, T., Krisimonika, D. I., Salean, D. D. C., & Priyandani, Y. (2021). PERILAKU MAHASISWA TERKAIT CARA MENGATASI JERAWAT. Jurnal Farmasi Komunitas, 8(1), 15–19. https://doi.org/10.20473/JFK.V8I1.21922
Madelina, W., & Sulistiyaningsih, S. (2018). REVIEW: RESISTENSI ANTIBIOTIK PADA TERAPI PENGOBATAN JERAWAT. Farmaka, 16(2), 105–117. https://doi.org/10.24198/JF.V16I2.17665
Mamatha, D., Kaur, A., Madhu Sri, G., Maneesha, P., & Mounika, P. (2022). Formulation and Evaluation of a Poly Herbal Anti Acne Fruit Face Wash Gel Production and Hosted by Pharmasprings.com. In Future J. Pharm. Health. Sci (Vol. 2022, Issue 1). https://pharmasprings.com//jphs
Melly Nirmala, F., Artikel, I., Sediaan Facial Wash Kombinasi Perasan Jeruk Lemon, F., Ayu Rai Saputri, G., & Marcellia, S. (2021). Formulasi Sediaan Facial Wash Kombinasi Perasan Jeruk Lemon (Citrus Limon (L.)) Dan Ekstrak Buah Tomat (Solanum lycopersicum L.) Sebagai Antibakteri Propionibacterium Acnes. Jurnal Mandala Pharmacon Indonesia, 7(2), 188–206. https://doi.org/10.35311/JMPI.V7I2.87
Nurul Fauziyah, R., & Widyasanti, A. (2021). The valorization of neem leaves infused coconut oil at various concentrations for the production of natural liquid shampoo. Advances in Food Science, Sustainable Agriculture and Agroindustrial Engineering, 4(2), 131–137. https://doi.org/10.21776/UB.AFSSAAE.2021.004.02.6
Rasyadi, Y., Yenti, R., & Jasril, A. P. (2019). Formulasi dan Uji Stabilitas Fisik Sabun Mandi Cair Ekstrak Etanol Buah Kapulaga (Amomum compactum Sol. ex Maton). PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia), 16(2), 188–198. https://doi.org/10.30595/PHARMACY.V16I2.5675
Rinaldi, Fauziah, & Rizka Mastura. (2021). FORMULASI DAN UJI DAYA HAMBAT SABUN CAIR EKSTRAK ETANOL SERAI WANGI (Cymbopogon nardus L) TERHADAP PERTUMBUHAN Staplylococcus aureus.
S. H. Annisa. (2018). FORMULASI DAN UJI STABILITAS FACE WASH GEL EKSTRAK ETANOL DAUN KERSEN (Muntingia Calabura L) SEBAGAI ANTI JERAWAT.
Sri, R. D. P. (2017). FORMULASI DAN EVALUASI MUTU FISIK SABUN DARI EKSTRAK RUMPUT LAUT MERAH (Euchema cottoni). Jurnal Wiyata: Penelitian Sains Dan Kesehatan, 2(1), 14–18. https://doi.org/10.56710/WIYATA.V2I1.29
Studi Biologi, P., Mipa, F., Tanjungpura, U., Hadari Nawawi, J. H., Angelina, M., Turnip, M., & Khotimah, S. (2015). Uji Aktivitas Antibakteri Ekstrak Etanol Daun Kemangi (Ocimum sanctum L.) Terhadap Pertumbuhan Bakteri Escherichia coli dan Staphylococcus aureus (Vol. 4, Issue 1).
Wulandini, R., Irwansyah, F. S., & Windayani, N. (2019). Formulation of facial cleansing gels using aloe vera as natural surfactant. Journal of Physics: Conference Series, 1402(5). https://doi.org/10.1088/1742-6596/1402/5/055069
Yuniarsih, N., Akbar, F., Lenterani, I., Fakultas Farmasi, F., Buana Perjuangan Karawang, U., & Barat, J. (2020). FORMULASI DAN EVALUASI SIFAT FISIK FACIAL WASH GEL EKSTRAK KULIT BUAH NAGA MERAH (Hylocereus polyrhizus) DENGAN GELLING AGENT CARBOPOL. Pharma Xplore : Jurnal Sains Dan Ilmu Farmasi, 5(2), 57–67. https://doi.org/10.36805/JPX.V5I2.1194
Yuniarsih, N., Lenterani, I., & Farhamzah. (2021). Formulation and Physical Stability Test of Facial Gel Wash Dragon Fruit (hylocereus polyrhizus) Peel Extract. IOP Conference Series: Materials Science and Engineering, 1071(1), 012012. https://doi.org/10.1088/1757-899x/1071/1/012012