Relationship Between Anti-Virus Drugs And The Incidence Of Herpes Zoster Oticus: Literature Review
Keywords:
Herpes Zoster Oticus , Ramsay Hunt Syndrome, Anti-viral .Abstract
Herpes zoster oticus (HZO) is an infectious disease characterized by an erythematous vesicular eruption or rash on the pinna and external auditory canal along with severe otalgia. Antiviral drugs are very effective in reducing the severity and duration of HZO when treatment is started within 72 hours of the onset of the rash. Objective: This retrospective study summarizes the knowledge of the relationship of antiviral therapy to the incidence of Herpes Zoster Oticus . Method: This article is a literature study or literature review. The literature was obtained by collecting and reviewing Narrative Review, Case Report, Journal Method articles that were downloaded using electronic based accredited/indexed by Scopus and Sinta. Results: In this literature, 20 research articles were obtained discussing herpes zoster oticus and in them discussing treatment using antivirals. Among them consisted of 8 Case reports, 6 Narrative Reviews, and 6 Journal Methods. Conclusion: Antiviral administration in the occurrence of Herpes Zoster Oticus Antiviral administration in cases of Herpes Zoster Oticus is still effective until now. Administration of antivirals as early as possible within 72 hours is effective in reducing the severity of Herpes zoster oticus . Early treatment can stop the invasion and replication of the Varicella zoster virus further into the cranial nerves so that the prognosis for healing nerve function is very good. The combination of Antivirals and corticosteroids is the standard treatment for Herpes zoster oticus which helps full recovery of facial paralysis and inhibits hearing loss. However, from this literature review it is known that the delay in treatment of hearing function experienced will continue.
References
Choi, J. M., Shin, J. E. and Kim, C. (2012) ‘A Case of Herpes Zoster Oticus without Facial Nerve Palsy Associated with Vertigo and Hearing Loss’, 11(4), pp. 138–141.
Devi, M. et al. (2022) ‘Penegakan Diagnosis dan Penatalaksanaan Herpes Zoster’, Medical Profession Journal of Lampung, 12(1), pp. 40–48. doi: 10.53089/medula.v12i1.330.
Dwitasari, M. A. D. and Seputra, D. M. C. S. (2023) ‘Ramsay Hunt syndrome : A Case Report’, Indian Journal of Dermatology, Venereology and Leprology, 9(1), pp. 70–72. doi: 10.21776/ub.mnj.2023.009.01.15.
Goswami, Y. and Gaurkar, S. S. (2023) ‘Ramsay Hunt Syndrome: An Introduction, Signs and Symptoms, and Treatment’, Cureus, 15(1), pp. 1–7. doi: 10.7759/cureus.33688.
Kansu, L. and Yilmaz, I. (2012) ‘Herpes Zoster Oticus (Ramsay Hunt syndrome) in Children: Case Report and Literature Review’, International Journal of Pediatric Otorhinolaryngology. Elsevier Ireland Ltd, 76(6), pp. 772–776. doi: 10.1016/j.ijporl.2012.03.003.
Kim, J. M. et al. (2018) ‘Treatment of Ramsay-Hunt’s syndrome with multiple cranial nerve involvement and severe dysphagia’, Medicine (United States), 97(17). doi: 10.1097/MD.0000000000010591.
Kinishi, M. et al. (2001) ‘Acyclovir Improves Recovery Rate of Facial Nerve Palsy in Ramsay Hunt Syndrome’, Auris Nasus Larynx, 28(3), pp. 223–226. doi: 10.1016/S0385-8146(01)00055-4.
Ko, J. Y., Sheen, T. S. and Hsu, M. M. (2000) ‘Herpes Tester Oticus Treated with Acyclovir and Prednisolone: Clinical Manifestations and Analysis of Prognostic Factors’, Clinical Otolaryngology and Allied Sciences, 25(2), pp. 139–142. doi: 10.1046/j.1365-2273.2000.00336.x.
Kumar, A. et al. (2024) ‘Herpes Zoster Oticus - A Rare Case Report’, International Journal of Scientific Research, 13(04), pp. 22–24.
Monogr, V., Basel and Karger (2006) (Herpes) Zoster Oticus, Monographs in Virology ·. doi: 10.1159/000096256.
Murakami, S. et al. (1997) ‘Treatment of Ramsay Hunt Syndrome with Acyclovir-Prednisone: Significance of Early Diagnosis and Treatment’, Annals of Neurology, 41(3), pp. 353–357. doi: 10.1002/ana.410410310.
Patil, A., Goldust, M. and Wollina, U. (2022) ‘Herpes zoster: A Review of Clinical Manifestations and Management’, Viruses, 14(2), pp. 1–13. doi: 10.3390/v14020192.
Pitton Rissardo, J. and Fornari Caprara, A. L. (2018) ‘Herpes Zoster Oticus, Ophthalmicus, and Cutaneous Disseminated: Case Report and Literature Review’, Neuro-Ophthalmology. Taylor & Francis, 43(6), pp. 1–4. doi: 10.1080/01658107.2018.1523932.
Rim, H. S. et al. (2023) ‘Herpes Zoster Oticus with Concurrent Hearing Loss: A Study on Clinical Characteristics and Prognosis’, Journal of Clinical Medicine, 12(20). doi: 10.3390/jcm12206476.
Rouihi, A. et al. (2022) ‘Clinical and therapeutic features of herpes zoster oticus: a case report’, Pan African Medical Journal, 41. doi: 10.11604/pamj.2022.41.171.33711.
Swain, S. K. and Paul, R. R. (2021) ‘Herpes Zoster Oticus: A Morbid Clinical Entity Santosh’, MAMC Journal of Medical Sciences, 7(2), pp. 99–103. doi: 10.4103/mamcjms.mamcjms.
Teggi, R. et al. (2023) ‘Cochleo-Vestibular Disorders in Herpes Zoster Oticus: A Literature Review and a Case of Bilateral Vestibular Hypofunction in Unilateral HZO’, Journal of Clinical Medicine, 12(19). doi: 10.3390/jcm12196206.
Uri, N. et al. (2003) ‘Acyclovir in The Treatment of Ramsay Hunt Syndrome’, Otolaryngology - Head and Neck Surgery, 129(4), pp. 379–381. doi: 10.1016/S0194-5998(03)01305-6.
Waldman, R. A. et al. (2015) ‘Ramsay Hunt Syndrome Type 2: A Review of an Uncommon and Unwelcome Neurodermatologic Disease’, Journal of Otolaryngology and Rhinology, 1(1). doi: 10.23937/2572-4193.1510003.