Standardization of Anthocyanin Compounds in Plants in Indonesia: Literature Review

Annastya Eka Agustin; Vriezka  Mierza; Bunga Nur Annisa; Cantika Nurul Sa’adah; Fajar Prasetyo; Christina Febiola Lubis

Authors

Annastya Eka Agustin Universitas Singaperbangsa Karawang
Vriezka Mierza Universitas Singaperbangsa Karawang
Bunga Nur Annisa Universitas Singaperbangsa Karawang
Cantika Nurul Sa’adah Universitas Singaperbangsa Karawang
Fajar Prasetyo Universitas Singaperbangsa Karawang
Christina Febiola Lubis Universitas Singaperbangsa Karawang

Keywords:

Antocyanins, Standardization, Plants

Abstract

Anthocyanins are secondary metabolites belonging to the flavonoid group which act as pigments or coloring agents in plants that give red, blue and purple colors to flowers, fruits and vegetables. Anthocyanins have several pharmacological activities such as antioxidants, anti-carcinogenic, preventing impaired liver function, anti-hypertensive, and anti-diabetic. The anthocyanin structure consists of an aglycone form which is sterified by several sugar groups (glycones) and acyl groups in several anthocyanin compounds. In an effort to maintain the standard of a drug made from natural ingredients, the process of standardization of active compounds can be carried out to guarantee and maintain safety, quality uniformity and efficacy. This review was conducted to identify the anthocyanins contained in an extract by means of thin layer chromatography (TLC), UV-Vis spectrophotometer, thin layer chromatography-densitometry, and high performance liquid chromatography (HPLC). The research methodology used is in the form of literature review with reference sources related to the review topic obtained from various sources, such as Pubmed, Science Direct, and Google Scholar.

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