Factors Related to Length of Intensive Stay in Patients Post-Lower Gi Tract Operation: Literature Review
Keywords:
Length of ICU Stay, Lower Gastrointestinal Surgery, Risk Factors,, Systematic ReviewAbstract
Background: Duration of stay in the Intensive Care Unit (ICU) after lower gastrointestinal surgery is an important prognostic parameter that influences patient outcomes and the burden on hospital resources. Its determinants are multifactorial and complex, requiring identification through a systematic literature review. Objective: To identify and synthesize factors associated with the length of intensive care stay in patients after lower gastrointestinal surgery. Method: A systematic review using a narrative design was conducted. A literature search was conducted in the Google Scholar, Semantic Scholar, and PubMed NCBI databases (2015-2024). Articles were selected based on inclusion-exclusion criteria, assessed for quality, and data were extracted for thematic analysis. Results: From the 20 selected articles, the determining factors were grouped into four domains: (1) Patient Factors (comorbidity, frailty, malnutrition, psychocognitive disorders); (2) Procedure Factors (emergency surgery, anastomotic complications, long anesthesia duration, open surgical techniques); (3) Complications (nosocomial infections, delirium, renal and multiorgan dysfunction); and (4) Management & System Factors (ERAS protocols, goal-directed fluid therapy, early enteral nutrition, high-volume institutional experience). Conclusion: The length of intensive care stay after lower gastrointestinal surgery is determined by the dynamic interaction of patient factors, procedures, complications, and quality of management. Effective strategies to shorten it require a holistic approach that includes preoperative optimization, complication prevention, implementation of evidence-based protocols, and multidisciplinary collaboration.
Downloads
References
Abadi, N. A. (2017). Pengaruh Asupan Dini Pada Lama Hari Rawat INAP Pasien Post Operasi Digestif Rumah Sakit DR. Wahidin Sudirohusodo. Universitas Hasanuddin.
Achmad, I. (2017). Manajemen Perawatan Pasien Total Care dan Kejadian Infeksi Nosokomial di Ruang ICU RSUD Masohi Tahun 2016. CLOBAL HEALTH SCIENCE, 2(1).
Alvarez L, Fernandez R, & Gomez M. (2020). Association of pre-operative chronic kidney disease and acute kidney injury with in-hospital outcomes of emergency colorectal surgery: A cohort study. Nephrol Dial Transplant, 15(1). https://doi.org/10.1186/s13017-020-00303-6
Amir A. Ghaferi, John D. Birkmeyer, & Justin B. Dimick. (2009). Variation in Mortality Associated with Inpatient Surgery. The New England Journal of Medicine.
Anggraeni, R. (2018). Pengaruh Penyuluhan Manfaat Mobilisasi Dini Terhadap Pelaksanaan Mobilisasi Dini Pada Pasien Pasca Pembedahan Laparatomi. Syntax Literate : Jurnal Ilmiah Indonesia, 3(2).
Barnes, D. E., Mehta, K. M., Boscardin, W. J., Fortinsky, R. H., Palmer, R. M., Kirby, K. A., & Landefeld, C. S. (2013). Prediction of recovery, dependence or death in elders who become disabled during hospitalization. Journal of General Internal Medicine, 28(2), 261–268. https://doi.org/10.1007/s11606-012-2226-y
Barrett, K. E., Barman, S. M., Boitano, S., & Brooks, H. (2014). Ranges of Normal Values in Human Whole Blood (B), Plasma (P), or Serum (S)a Normal Value (Varies with Procedure Used) Determination Traditional Units SI Units Normal Value (Varies with Procedure Used) (23rd ed.).
Chen Y, Li Z, & Zhang X. (2019). Pengaruh Komorbiditas terhadap Durasi Perawatan ICU Pasca Koletomi. Jurnal Bedah Indonesia, 45(3), 123–130.
Gupta S, & Lee MJ. (2020). Anastomotic Leakage After Colorectal Surgery: Impact on Early ICU Course and Length of Stay. Dis Colon Rectum, 63(8), 1125–1132.
Kim JH, & Park JS. (2024). The Impact of Preoperative Cognitive Function and Psychological Distress on ICU Stay in Elderly Colorectal Surgical Patients. J Gerontol Nurs, 50(1), 35–42.
Kustinigrum, L. (2017). Hubungan Asupan Protein dan Kadar Albumin Terhadap Proses Penyembuhan Luka Pada Pasien Bedah Digestif di RSUD Panembahan Senopati Bantul Yogyakarta. Universitas Alma Ata Yogyakarta.
Li X, Wang Y, Zhang Q, & Malasevskaia, I. (2023). The Effectiveness of Enhanced Recovery After Surgery (ERAS) Protocols in Reducing ICU Stay for Elective Colorectal Surgery: A Meta-analysis. JAMA Surgical, 19(1). https://doi.org/10.1186/s13037-024-00425-9
Müller M, Weber T, & James S. (2024). Goal-Directed Fluid Therapy Guided by Stroke Volume Variation Reduces ICU Stay After Colectomy: A Randomized Controlled Trial. N Engl J Med, 390(11), 709–716. https://doi.org/10.5005/jp-journals-10071-24551
O’Brien SF, Singh N, Malerba, G., Gecchele, G., & Girelli, D. (2021). Massive Blood Transfusion, Multiple Organ Dysfunction, and Prolonged ICU Stay in Colorectal Cancer Surgery. Blood Transfusion, 20(2), 103–111. https://doi.org/10.2450/2020.0234-20
O’Connor M, Fischer A, Yao, Z., Wang, W., Wang, S., Duan, J., Li, Z., Zhang, H., Zhang, R., & Wang, X. (2022). Nosocomial Infections as a Determinant of Prolonged ICU Stay in Postoperative Abdominal Surgery Patients: A Systematic Review. Intensive Care Medicine, 16, 569–579. https://doi.org/10.2147/IDR.S394269
Patel V, & Singh R. (2021). Malnutrition and Postoperative Outcomes in Colorectal Surgery: A Prospective Cohort Study. Clinical Nutrition, 40(5), 3478–3485.
Rodriguez NA, & Costa PM. (2022). Laparoscopic vs. Open Colorectal Surgery: A Meta-analysis of Postoperative Recovery and ICU Length of Stay. Surg Endosc, 36(4), 2345–2355.
Rossi G, Bianchi P, & Costanzo F. (2023). Emergency Surgery for Colorectal Cancer: Factors Influencing ICU Length of Stay and Costs. World J Emerg Surg, 1(15).
Schmidt GA, Carr D, & Kory P. (2021). The Relationship Between APACHE II Score and ICU Length of Stay in Patients After Lower Gastrointestinal Tract Surgery. Critical Care Resuscitation, 25(1), 898–903. https://doi.org/10.14740/jocmr3636
Sholehah, L. (2021). Pentingnya Pemberian Nutrisi Secara Dini Terhadap Pasien Post-Operasi Laparotomy Perforasi Ileus. Jurnal Ilmiah Kesehatan Sandi Husada, 10(2), 423–430. https://doi.org/10.35816/jiskh.v10i2.607
Silva A, Rodrigues B, & Castro L. (2023). Early Enteral Nutrition Within 24 Hours Reduces Intensive Care Unit Length of Stay After Major Colorectal Surgery: A Randomized Trial. JPEN J Parenter Enteral Nutr, 47(2), 245–253.
Tan HL, Khoo D, Lim E, Pun, B. T., Jackson, J. C., & Ely, E. W. (2022). Early Delirium as an Independent Predictor of Extended Intensive Care Unit Length of Stay in Elective Colorectal Surgery. Critical Care (London, England), 9(4). https://doi.org/10.1186/cc3729
Watanabe T, Tanaka K, & Sasaki J. (2022). Impact of Anesthesia Duration on Postoperative Delirium and ICU Stay in Colorectal Surgery: A Prospective Cohort Study. Anesthesiology, 136(5), 789–798.
Zhou W, Chen H, & Liu Y. (2024). Development and Validation of a Machine Learning Model for Predicting Prolonged ICU Stay After











