Antioxidant Testing of Solid Soap Preparations Containing Ethanol Extract from California Papaya Leaves (Carica Papaya L.)

Authors

  • Gabriela Reyna Rumi Pharmacy Study Program, Faculty of Applied Sciences, Muhammadiyah Sorong University of Education, Sorong, Indonesia
  • Ratih Arum Astuti Pharmacy Study Program, Faculty of Applied Sciences, Muhammadiyah Sorong University of Education, Sorong, Indonesia
  • Irwandi Irwandi Pharmacy Study Program, Faculty of Applied Sciences, Muhammadiyah Sorong University of Education, Sorong, Indonesia

Keywords:

Papaya Leaves, Solid Soap Preparation, Antioxidant

Abstract

Air pollution is a global environmental problem that is getting worse due to the mixing of natural atmospheric components with pollutants from human and natural activities. One of the main causes of air pollution in Southwest Papua is the increase in the number of motor vehicles, especially in cities such as Sorong, which also contributes to increased pollutant emissions. One plant that has antioxidant activity is papaya, which contains flavonoids, tannins, and alkaloids. Papaya (Carica papaya L) is a fruit from the Caricaceae family. This study aims to test and determine the antioxidant activity in solid soap preparations and preparation concentrations. This study uses two concentrations, namely 8% and 24%. Positive control used quercetin as a comparison. The results of the study conducted on 8% concentration solid soap preparations showed an IC50 value of 37.77, while 24% concentration preparations showed an IC50 value of 36.81. From the results obtained, it can be concluded that California papaya leaf ethanol extract solid soap preparations have high antioxidant activity When compared to the positive control quercetin, the IC₅₀ value of quercetin is 0.93 ppm, meaning that the positive control quercetin has stronger antioxidant activity.

References

Asyhar, R., & Minarni. (2023). Berorientasi Green Chemistry Dengan Mengimplementasikan Project Based Learning.

Dalimunthe, G. I., Sutrisna, B., Rani, Z., & Ginting, O. S. B. (2024). FORMULASI DAN EVALUASI SEDIAAN SABUN SARI PEPAYA (Carica papaya L) SEBAGAI PELEMBAB. Forte Journal, 04(01), 251–260.

Depkes RI. 1995. Materia Medika Indonesia Jilid VI. Jakarta: Departemen Kesehatan Dominica, D. Dan Handayani, D. 2019. Formulasi Dan Evaluasi Sediaan Lotion Dari Ekstrak

Daun Lengkeng (Dimocarpus Longan) Sebagai Antioksidan. Jurnal Farmasi Dan Ilmu Kefarmasian Indonesia. 6. (1).

Erawati, R., Muslihin, A. M., & Hardia, L. (2024). Uji Aktivitas Antioksidan Fraksi Ekstrak Etanol Tali Kuning (Anamirta Cocculus) Dengan Metode DPPH. Jurnal Promotif Preventif, 7(2), 381–391.

Haerani, A., Chaerunisa, A. Y., & Subarnas, A. (2018). ARTIKEL TINJAUAN: ANTIOKSIDAN UNTUK KULIT. Farmaka, 16(2), 135–151.

Hani, R. C., & Milanda, T. (2016). REVIEW: MANFAAT ANTIOKSIDAN PADA TANAMAN BUAH DI INDONESIA. Farmaka, 14(1), 184–190.

Muslihin, A. M., And Ratih Arum Astuti. 2022. “Analisis Aktivitas Antioksidan Fraksi Ekstrak Daun Mimba (Azadirachta Indica A.Juss) Dengan Metode DPPH.”

Panche, A.N., Diwan, A.D., & Chandra, S.R. (2016). Flavonoids: an overview. Journal of Nutritional Science, 5, e47.

Rahmawati, S., & Pratama, I. N. (2023). Pengaruh penggunaan transportasi berkelanjutan terhadap kualitas udara dan kesejahteraan masyarakat. Journal of Enviromental Policy and Technology, 1(2), 9–10.

Republik Indonesia, pp. 334, 336, 337.

Santi, I., Abidin, Z., & Asnawi, N. (2021). AKTIVITAS ANTIOKSIDAN DARI

TUMBUHAN PEPAYA (Carica papaya L.). As-Syifaa Jurnal Farmasi, 13(2), 102–107.

Santos-Sánchez, N.F., Salas-Coronado, R., Hernández-Carlos, B., & Villanueva-Cañongo, C. (2019). Antioxidant compounds and their antioxidant mechanism.

Serrano, J., Puupponen-Pimiä, R., Dauer, A., Aura, A.M., & Saura-Calixto, F. (2019). Tannins: Current knowledge of food sources, intake, bioavailability, and biological effects.

Molecular Nutrition & Food Research, 63(2), 1800048.

Silvia, D., Katharina, K., Hartono, S. A., Anastasia, V., & Susanto, Y. (2016).

PENGUMPULAN DATA BASE SUMBER ANTIOKSIDAN ALAMI. Journal of Technology, 1(2), 181–198.

Statistik, B. P. (2022). Statistik Lingkungan Hidup. Sorong: BPS Papua Barat Daya. Badan Pusat Statistik Provinsi Papua Barat Daya.

Suhartini, S., Hidayati, S., & Rahmawati, F. (2021). Analisis Kualitas Udara di Kota Sorong, Papua Barat. Jurnal Ilmu Lingkungan.

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Published

2025-11-14

How to Cite

Gabriela Reyna Rumi, Ratih Arum Astuti, & Irwandi, I. (2025). Antioxidant Testing of Solid Soap Preparations Containing Ethanol Extract from California Papaya Leaves (Carica Papaya L.). Jurnal EduHealth, 16(04), 1751–1758. Retrieved from https://ejournal.seaninstitute.or.id/index.php/healt/article/view/7311

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