Oral Manifestations in Patients with Down's Syndrome and Management in Prosthodontics

Authors

  • Achmad Syawqie Universitas Padjadjaran
  • Jennifer Putri Universitas Padjadjaran
  • Stephanie Yessica Universitas Padjadjaran
  • Nuroh Najmi Universitas Padjadjaran https://orcid.org/0000-0001-7214-1310

Abstract

Down syndrome is an autosomal disorder associated with involving mental and physical changes. The types of craniofacial phenotypes and dental anomalies in individuals with Down syndrome have been described extensively, but further elaboration of their impact of oral and craniofacial conditions still needs to be understood. In addition, in prosthodontic, oral rehabilitation with complete dentures and implants in patients with Down's syndrome still needs to be studied. The aim of this review is to describe that the oral and craniofacial manifestations may occur in patients with Down syndrome, and determine the effectiveness of oral rehabilitation treatments in patients with Down syndrome. The article was   conducted of two databases and were limited to the period from January 2016 to February 2022 with a combination of the following keywords: “Down Syndrome”, “oral manifestation”, “implant”, “prosthodontic treatment”. The results obtained were 194 articles found at the beginning of the search in both databases, and the 16 full text articles were selected for further review and discussion. The results of this study shows that Down syndrome causes several oral and craniofacial manifestations, dental caries risk, higher periodontal disease, dental abnormalities, soft and occlusal tissue, and the presence of a craniofacial complex. In prosthodontics, the choice of using removable dentures or implants must be adjusted to each patient's condition. Down syndrome is an autosomal disorder that has oral and craniofacial manifestations that must be a concern for health practitioners, especially dentists. In prosthodontics, oral rehabilitation with either complete dentures or implants in patients with Down's syndrome is the right choice, but it is necessary to consider the complications that may occur.

References

Contaldo M. Santoro R. Romano A. Loffredo F. Stasio DD. Vella FD, et al. Oral manifestations in children and young adults with Down Syndrome: A systematic review of the literature. Appl. Sci. 11(2021):1-15.

Sales PH. Barros AWP. Lima FJ. Carvalho AA. Leao JC. Is Down Syndrome a risk factor or contraindication for dental implants? A Systematic Review. The Journal of Prosthetic Dentistry (2021): 1-7.

Sajjanar, et al. Dohsa-Hou therapeutic approach of completely edentulous Down Syndrome patient before rehabilitation with a dental prosthesis-a case report. Annals of R.S.C.B 25.4 (2021): 8247-53.

Kazemi M, Salehi M, Kheriollahi M. Down syndrome: current status, challenges, and future perspectives. Int J Mol Cell Med. 2016;5(3):125-133.

Antonarakis SE. Down syndrome and the complexity of genome dosage imbalance. Nat Rev Genet. 2017;18(3):147-163

Coppede F. Risk factors for Down syndrome. Toxicology. 2016;90(12):2917-2929.

Mubayrik AB. The dental needs and treatment of patients with Down Syndrome. Dent Clin N Am 60(2016):613-26.

Wen X, et al. History of periodontitis as a risk factor for long-term survival of dental implants: A meta-analysis. Int J Oral Maxillofac Implants 29 (2014):1271-1280.

Baus-Domínguez M, et al. Metallothioneins in failure of dental implants and periodontitis Down Syndrome patients. Genes (Basel) 10 (2019): 711.

Baus-Domínguez M, et al. using genetics in periodontal disease to justify implant failure in Down Syndrome patients. J Clin Med 9 (2020): 2525.

Porovic S, et al. Oral health of Down Syndrome adults in Bosnia and Herzegovina. Mater Sociomed 28 (2016): 437-9.

Corcuera-Flores JR, et al. Four years survival and marginal bone loss of implants in patients with Down Syndrome and Cerebral Palsy. Clin Oral Investig 21 (2017): 1667-1674.

Posse JL, et al. Survival of dental implants in patients with Down Syndrome: A Case Series. J Prosthet Dent (2016): 880-4.

Jenny N, et al. Know About Biocompatibility of Dental Materials : A Review. Pyrex J Med Med Sci. (2017): 33-43.

Anzalone JV, et al. Oroantral Communication as an Osteotome Sinus Evelation Complication. J Oral Implantol. (2019): 231-7.

Abraham HM, et al. Use of Chlorhexidine in Implant Dentistry. Biomedical & Pharmacology Journal. (2018): 341-5.

Downloads

Published

2023-01-31

How to Cite

Syawqie, A., Putri, J., Yessica, S., & Najmi, N. (2023). Oral Manifestations in Patients with Down’s Syndrome and Management in Prosthodontics. Jurnal EduHealth, 14(01), 115–122. Retrieved from https://ejournal.seaninstitute.or.id/index.php/healt/article/view/1263

Most read articles by the same author(s)