The Role of Nutrition on the Immune Response

Authors

  • Felisha Febriane Balafif Universitas Padjadjaran
  • Anggun Rafisa Universitas Padjadjaran
  • Faisal Kuswandani Universitas Padjadjaran
  • Nuroh Najmi Universitas Padjadjaran

Keywords:

Immune response, nutrition, role

Abstract

The immune system reaction against infections and other foreign substances is known as the immune response. Nutrition is a critical component in the modulation of the immune system, hence the importance of a balanced diet. Better nutrition improves health, reinforces the immune system, contributes to longevity, and decreases the chance of non-communicable diseases. Thus, nutrition, health, and immune system are strongly connected. The aim of the present study is to evaluate current knowledge on the role of nutrition on the immune response. The article was conducted of two databases and were limited to the period from January 2018 to April 2023 with a combination of the following keywords: “role" and "nutrition" and "immune response. The results obtained were 17 articles found at the beginning of the search in both databases, and the 10 full text articles were selected for further review and discussion. The results of this study shows that immunonutrition plays a role in immune function. Nutrition such as vitamins A, B6, B12, C, D, E, and folate; and trace elements (zinc, iron, selenium, magnesium, and copper) play important and complementary roles in supporting both the innate and adaptive immune systems. The development and maintenance of our immune system are very intricately tied to our dietary pattern. Therefore, working on our food habits and improving our nutrition seem to be a pragmatic approach to strengthen our immune response. Multiple micronutrients play vital roles in supporting the immune response.

Author Biographies

Felisha Febriane Balafif, Universitas Padjadjaran

 

 

Anggun Rafisa, Universitas Padjadjaran

 

 

Faisal Kuswandani, Universitas Padjadjaran

 

 

Nuroh Najmi, Universitas Padjadjaran

 

 

References

M. Casarin, T. M. da Silveira, B. Bezerra, F. Q. Pirih, and N. M. Pola, “Association between different dietary patterns and eating disorders and periodontal diseases,” Frontiers in Oral Health, vol. 4, Mar. 2023, doi: 10.3389/froh.2023.1152031.

A. A. Justiz Vaillant, S. Sabir, and A. Jan, Physiology, Immune Response. 2023.

L. A. Denson, “The Role of the Innate and Adaptive Immune System in Pediatric Inflammatory Bowel Disease,” Inflamm Bowel Dis, p. 1, May 2013, doi: 10.1097/MIB.0b013e318281f590.

H. Lawrence, A. E. Mawdesley, J. P. Holland, J. A. Kirby, D. J. Deehan, and A. J. Tyson-Capper, “Targeting Toll-like receptor 4 prevents cobalt-mediated inflammation,” Oncotarget, vol. 7, no. 7, pp. 7578–7585, Feb. 2016, doi: 10.18632/oncotarget.7105.

A. Arce-Sillas et al., “Regulatory T Cells: Molecular Actions on Effector Cells in Immune Regulation,” J Immunol Res, vol. 2016, pp. 1–12, 2016, doi: 10.1155/2016/1720827.

F. V. Zohoori, “Chapter 1: Nutrition and Diet,” 2020, pp. 1–13. doi: 10.1159/000455365.

P. Martinon, L. Fraticelli, A. Giboreau, C. Dussart, D. Bourgeois, and F. Carrouel, “Nutrition as a Key Modifiable Factor for Periodontitis and Main Chronic Diseases,” J Clin Med, vol. 10, no. 2, p. 197, Jan. 2021, doi: 10.3390/jcm10020197.

E. L. Cooper and M. J. Ma, “Understanding nutrition and immunity in disease management,” J Tradit Complement Med, vol. 7, no. 4, pp. 386–391, Oct. 2017, doi: 10.1016/j.jtcme.2016.12.002.

H. Pahwa and K. Sharan, “Food and nutrition as modifiers of the immune system: A mechanistic overview,” Trends Food Sci Technol, vol. 123, pp. 393–403, May 2022, doi: 10.1016/j.tifs.2022.03.017.

A. F. Gombart, A. Pierre, and S. Maggini, “A Review of Micronutrients and the Immune System-Working in Harmony to Reduce the Risk of Infection.,” Nutrients, vol. 12, no. 1, Jan. 2020, doi: 10.3390/nu12010236.

P. Calder, A. Carr, A. Gombart, and M. Eggersdorfer, “Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections,” Nutrients, vol. 12, no. 4, p. 1181, Apr. 2020, doi: 10.3390/nu12041181.

P. C. Calder, “Nutrition, immunity and COVID-19,” BMJ Nutr Prev Health, vol. 3, no. 1, pp. 74–92, Jun. 2020, doi: 10.1136/bmjnph-2020-000085.

A. F. Gombart, A. Pierre, and S. Maggini, “A Review of Micronutrients and the Immune System–Working in Harmony to Reduce the Risk of Infection,” Nutrients, vol. 12, no. 1, p. 236, Jan. 2020, doi: 10.3390/nu12010236.

S. Santonocito et al., “A Cross-Talk between Diet and the Oral Microbiome: Balance of Nutrition on Inflammation and Immune System’s Response during Periodontitis,” Nutrients, vol. 14, no. 12, p. 2426, Jun. 2022, doi: 10.3390/nu14122426.

F. Pecora, F. Persico, A. Argentiero, C. Neglia, and S. Esposito, “The Role of Micronutrients in Support of the Immune Response against Viral Infections,” Nutrients, vol. 12, no. 10, p. 3198, Oct. 2020, doi: 10.3390/nu12103198.

Childs, Calder, and Miles, “Diet and Immune Function,” Nutrients, vol. 11, no. 8, p. 1933, Aug. 2019, doi: 10.3390/nu11081933.

S. Santonocito et al., “A Cross-Talk between Diet and the Oral Microbiome: Balance of Nutrition on Inflammation and Immune System’s Response during Periodontitis,” Nutrients, vol. 14, no. 12, p. 2426, Jun. 2022, doi: 10.3390/nu14122426.

M. Di Costanzo, N. De Paulis, M. E. Capra, and G. Biasucci, “Nutrition during Pregnancy and Lactation: Epigenetic Effects on Infants’ Immune System in Food Allergy,” Nutrients, vol. 14, no. 9, p. 1766, Apr. 2022, doi: 10.3390/nu14091766.

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Published

2023-05-29

How to Cite

Febriane Balafif, F., Rafisa, A., Kuswandani, F., & Najmi, N. (2023). The Role of Nutrition on the Immune Response. Jurnal EduHealth, 14(02), 630–634. Retrieved from https://ejournal.seaninstitute.or.id/index.php/healt/article/view/2056

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