Potential Protein Receptors in Enterococcus faecalis as Antibacterial and Anti-Biofilm Target Therapy in Endodontic treatment: A Review
Keywords:
Enterococcus faecalis, Antibacterial, Antibiofilm, Targeted therapyAbstract
E. Faecalis is responsible for 80−90% of hospital-acquired enterococcal infections and failed endodontic tretment. The emergence of E. Faecalis multidrug resistance including to common endodontic medication and its ability to form biofilms have significantly complicated its clinical management. Thereby the development of novel antibacterial and antibiofilm agents is essential. Identifying and targeting key proteins is critical for drug discovery and development. This review aims to provide a brief information about potential protein receptors in E. Faecalis that could serve as targets for antibacterial and antibiofilm therapies.
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